Mosdosi B, et al. - Experts examined the skin perfusion and heat-induced hyperaemia in comparison with the clinical severity and laboratory parameters of Raynaud’s phenomenon (RP) in adolescents. Findings demonstrated altered heat-induced cutaneous hyperaemia responses in association with the clinical severity and symptomatology. In contrast with healthy individuals, the heat-induced percentage increase from baseline to maximal blood flow appeared to be markedly greater in symptomatic RP adolescents. No alteration was noted in the laboratory parameters and neuropeptide plasma levels in any groups.