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Impact of renin‐angiotensin system blockers on mortality in veterans undergoing cardiac surgery

Journal of the American Heart Association May 12, 2021

Antoniak DT, et al. - Researchers undertook this retrospective cohort analysis to determine the impact of renin‐angiotensin system blocker (RASB) use with 30‐day and 1‐year mortality post-cardiac surgery. Data were obtained from the Veterans Affairs Surgical Quality Improvement Program and Corporate Data Warehouse. This study involved 37,197 veterans receiving elective coronary artery bypass grafting and or valve repair or replacement over a 10‐year period. Findings revealed reduced mortality in relation to continuation of preoperative RASBs as well as initiation before discharge, among veterans undergoing cardiac surgery. Given these results, consideration should be given to continuation of preoperative RASBs or initiation in the early postoperative period among patients receiving cardiac surgery.

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