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Impact of peripheral artery disease on prognosis after percutaneous coronary intervention: Outcomes from the multicenter prospective e-ULTIMASTER registry

Atherosclerosis Jan 27, 2022

Peripheral artery disease (PAD) patients have higher risk for (cardiac) death after percutaneous coronary intervention (PCI), but not target vessel or lesion repeat revascularizations. A higher risk clinical profile of the PAD cohort was evident.

  • The e‐ULTIMASTER registry was used to compare patients with and without known PAD undergoing PCI, and propensity-score was employed to adjust for differences between the groups.

  • Of 33,880 patients, 2,255 (6.7%) had PAD, and older age with a higher burden of comorbidities was present in PAD patients.

  • Less likelihood of presenting with STEMI and more chance of undergoing complex PCI was observed in patients with PAD.

  • PAD was independently linked with 41% elevated risk for target lesion failure.

  • A 75% and 103% higher risk for all cause death and for cardiac death, respectively, was observed.

  • Regarding the rates of stent thrombosis, clinically driven target lesion revascularization, or MI, there was no difference.

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