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Impact of moderate hyperchloremia on clinical outcomes in intracerebral hemorrhage patients treated with continuous infusion hypertonic saline: A pilot study

Critical Care Medicine Aug 24, 2017

Riha HM, et al. – This study investigated the effect of moderate hyperchloremia (chloride ≥ 115 mmol/L) on clinical outcomes in intracerebral hemorrhage patients treated with continuous IV infusion 3% hypertonic saline. Findings demonstrated that development of moderate hyperchloremia during treatment with continuous IV infusion 3% hypertonic saline was associated with higher rates of in–hospital mortality, with moderate hyperchloremia independently predicting in–hospital mortality.
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