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Impact of low-dose steroids on HbA1c levels and development of pre-diabetes and NODAT in non-diabetic renal transplant recipients on long-term follow-up

International Urology and Nephrology Dec 07, 2017

Tillmann FP, et al. - In a population comprising non-diabetic first renal transplant recipients followed for a long duration, researchers assessed the effect of 5 mg of prednisolone/day on HbA1c levels and its relation to the development of pre-diabetes and new-onset diabetes mellitus (NODAT). Findings demonstrated that use of 5 mg of prednisolone/day was associated with increased HbA1c levels and an increased risk of developing pre-diabetes, but not NODAT. In addition, factors that were related to an increased risk of developing NODAT included body mass index, age and the use of tacrolimus.
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