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Impact of insulin degludec in hospitalized patients with and without type 2 diabetes requiring parenteral/enteral nutrition: An observational study

Advances in Therapy May 27, 2018

Fatati G, et al. - In noncritical hospitalized patients with and without type 2 diabetes (T2DM) receiving enteral and/or parenteral nutrition (EN, PN), the researchers evaluated the impact of treatment with insulin degludec (IDeg) on mean blood glucose (BG) and glycemic variability. They assessed mean BG and glycemic variability from admission up to 7 days of hospitalization in consecutive cases with and without T2DM. They used percentage of coefficient of variation (CV) for glucose to express glycemic variability. This study represented the first proof-of-concept that IDeg in hospitalized patients with or without T2DM who require nutritional support has the potential to maintain stable levels of BG and reduce glycemic variability notwithstanding the small sample size and the lack of control group.
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