Shah SA, et al. - Via performing a randomized, double-masked, placebo-controlled crossover study that included 34 healthy volunteers, researchers determined the impact of energy drink consumption on electrocardiographic and hemodynamic parameters. They gave participants 32 oz of either energy drink A, energy drink B, or placebo for consumption within 60 minutes on 3 study days with a 6-day washout period in between. The maximum change from baseline in Bazett's corrected QT interval for drinks A, B, and placebo were +17.9±13.9, +19.6±15.8, and +11.9±11.1 ms, respectively. The investigators noted that peripheral and central systolic and diastolic blood pressure levels were statistically significantly different vs placebo. Overall, acute-consumption of energy drinks led to a significant prolongation of the QTc interval and a rise in blood pressure levels, according to findings. Hence, the researchers recommend improved vigilance and limitation of energy drink intake among individuals with acquired or congenital long QT syndrome as well as those with hypertension.