Bonaccio M, et al. - In this investigation involving 22,839 people from the Moli-sani Study (2005–2010), researchers investigated the effect of combined healthy lifestyle factors on survival in an adult general population and in high-risk groups. A total of 1,237 deaths occurred during 8.2 years of follow-up. According to findings, there was considerable impact on survival from the combined four healthy lifestyles (ie, abstention from smoking, adherence to Mediterranean diet, physical activity, and absence of abdominal obesity) both in the general population and among high-risk subgroups. A substantial proportion of this association was explained by inflammatory (eg, C-reactive protein) and novel biomarkers (eg, markers of cardiac damage) of cardiovascular disease risk.