del Arco CD, et al. - Given that several classification systems have been described for stratifying patients with gastric carcinoma (GC), researchers performed this retrospective study for identification of molecular markers and development of new classifications by analyzing data of 206 cases of GC diagnosed and surgically resected in the hospital between 2000 and 2017. For immunohistochemical (IHC) study, clinicopathological features of all cases were evaluated and tissue microarrays were constructed. Findings revealed that IHC classification was significantly associated with patient gender, gross morphology, Laurén classification, tumor necrosis, perineural infiltration, type of leading edge, and patient outcome. Based on molecular biomarkers, the application of IHC classifications in clinical practice can help in the stratification of GC patients.