Carmona EG, García-Giménez JA, Lopez-Mejías R, et al. - This study sought to increase the understanding of the genetic contribution to Kawasaki disease (kDa) and IgA vasculitis (IgAV) by performing the first comprehensive large-scale analysis on the genetic overlap between both pediatric vasculitis. Researchers examined a sum of 1,190 vasculitis patients and 11 302 healthy controls. Using an inverse variance meta-analysis, first, in the discovery phase, genome-wide data of 405 kDa patients and 6,252 controls and 215 IgAV patients and 1,324 controls, all of European origin, were combined. They have distinguished a new risk locus with pleiotropic effects on the two vasculitis of childhood analyzed. According to the findings, this locus represents the strongest non-HLA signal described for IgAV to date.