Zhou Y, et al. - A systematic review and meta-analysis are done to summarize the hypertension cure rate of unilateral adrenalectomy in primary aldosteronism (PA) patients. The outcome of this study uncovered that the hypertension cure rate for unilateral adrenalectomy in PA is not optimal. To verify the utility of potential preoperative predictors in developing a novel and effective prediction model, large clinical trials are required.