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Histopathological findings and increased D-dimer are predictive factors of systemic thromboses in eosinophilic granulomatosis with polyangiitis

The American Journal of Dermatopathology Dec 02, 2018

Kanno K, et al. - Researchers studied the possible relationship between the clinical features and histopathology of cutaneous lesions in eosinophilic granulomatosis with polyangiitis (EGPA; ie, Churg–Strauss syndrome) cases, focusing on systemic thrombogenic conditions like visceral infarction and deep vein thrombosis. Fourteen cases of EGPA diagnosed between 1977 and 2017 at the Department of Dermatology at the Medical University of Asahikawa were clinically and histopathologically examined. The elevation of plasma D-dimer concomitant systemic thrombotic symptoms was significantly correlated. The histopathological finding of thrombotic characteristics and increased plasma D-dimer were predictors of EGPA accompanied by systemic thromboses like deep vein thromboses and cerebral infarction.
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