Liersch J, et al. - Via this study of 13 skin biopsy specimens collected from 13 people with measles and a review of cases in the literature, experts intended to distinguish characteristic histomorphological and immunohistochemical patterns of measles exanthema. Histopathological peculiarities of measles exanthema are quite unique and identified through a combination of multinucleated keratinocytes, and individual and clustered necrotic keratinocytes in the epidermis with proclaimed folliculosebaceous and acrosyringeal involvement. In verifying the diagnosis of measles, immunohistochemical staining of skin biopsies with anti-measles virus (MeV) nucleoprotein and anti-MeV phosphoprotein could be of high importance. For the immediate implementation of quarantine measures and for rendering, both methods could assist in immediate further diagnostic tools medical assistance, even in people in whom the clinician did not acknowledge measles as a differential diagnosis of the rash because of the rareness of the disease in a putatively vaccinated community.