Wang F, et al. - In this Retrospective analysis at Hospital of Zhejiang University, authors examined the influence of histopathologic parameters on the quality of life issues in outpatients with chronic rhinosinusitis (CRS). They recruited 120 cases of CRS who underwent endoscopic sinus surgery and collected their clinical features, CT evaluation, pre, and postoperative SNOT-22 scores along with histopathologic findings. They observed an improvement in symptoms. They found the adverse consequences of the presence of mucosal eosinophilia and basal membrane thickening on symptom control of surgical intervention.