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Higher triglyceride to high density lipoprotein cholesterol ratio increases cardiovascular risk: 10-year prospective study in a cohort of Chinese adults

Journal of Diabetes Investigation Jul 26, 2019

Chen Z, et al. - Over a 10-year follow-up period, researchers examined the association of triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio with cardiovascular (CV) risks among Chinese adults. The sample for this prospective study consisted of 96,542 patients in Kailuan, who were clustered through the median value (0.8533) of TG/HDL-C ratio. Through Cox proportional hazard models, the risk of CV events was estimated. There were 5,422 major CV events that took place during a median follow up of 9.75 years, including 1,312 myocardial infarction (MI) cases and 4,228 stroke cases. Data revealed that the cumulative incidence of MI, stroke and total CV events was 1.36%, 4.38% and 5.62%, respectively. Findings suggested that higher TG/HDL-C ratio among the Chinese population is associated with increased risks of major CV events.

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