Wen Y, Chen Z, Chen S, et al. - In this investigation involving 72 patients (mean age, 33.51 ± 7.05 years) with primary open-angle glaucoma and 36 healthy controls (mean age, 30.25 ± 6.70 years), researchers explored the effect of glaucomatous macular damage, specifically retinal ganglion cell (RGC) loss, on macular pattern vision measured by the vanishing optotype (VO) recognition contrast threshold. According to the results, the VO contrast threshold showed weak-to-moderate correlations with MS. In fovea-around VF, glaucomatous eyes have higher contrast thresholds for VO recognition. The VO contrast threshold is more vulnerable to RGC damage if the structure-function relationships are stronger.