Boehnke KF, et al. - In this investigation involving 989 adults who used cannabis every day for chronic pain, researchers ascertained if daily cannabis use frequency was correlated with pain severity and interference, quality of life measures relevant to pain (eg, anxiety and depressive symptoms), and cannabis use preferences (administration routes and cannabinoid ratio). According to this cross-sectional survey, lower daily cannabis use frequency is related to better clinical profile and safer use behaviors (eg, preference for cannabidiol and noninhalation administration routes). Such trends highlight the need for developing cannabis use guidelines for clinicians in order to better protect cannabis patients.