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High diagnostic yield of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the diagnosis of adolescent pulmonary tuberculosis

BMC Infectious Diseases Sep 17, 2021

Geweniger A, Janda A, Eder K, et al. - Findings demonstrate sensitivity as well as safety of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) along with its high diagnostic yield in the assessment of pediatric patients with mediastinal pathology and suspected tuberculosis (Tb).

  • This study involved 34 unaccompanied refugee minors, aged 14 to 17 years, with suspected pulmonary Tb.

  • EBUS-TBNA was conducted in 21 patients, and a high diagnostic yield was found: 66.7% positive results (M. tuberculosis identified either by acid-fast stain, culture or polymerase chain reaction in 4.8, 42.9 and 61.9% of samples, respectively).

  • No procedure-related complications occurred.

  • Pulmonary Tb, miliary Tb, and latent Tb were diagnosed in 29 patients (85.3%), two patients (5.9%), and in three patients (8.8%), respectively.

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