Wang M, et al. - Whether plasma microparticles (MPs) and tissue factor- positive microparticles (TF+MPs) can afford valuable predictors of venous thromboembolism (VTE) development in lung cancer, was determined in this case-control study utilizing the Beijing Chao-Yang Hospital Lung Cancer Registry. Cases included patients developing VTE 3 months prior to or following a diagnosis of lung cancer. Lung cancer cases without VTE matched for age, histology, and stage were included as controls. Patients with VTE vs those without VTE had a significantly more elevated proportion of MPs and TF+MPs. A significant link of MPs and adenocarcinoma with VTE was revealed in multivariate logistic regression analysis. In diagnosing VTE, the sensitivity and the specificity of the proportion of MPs was 93.3% and 70.0%, respectively, and these values for the proportion of TF+MPs were 66.7% and 88.3%, respectively. For the diagnostic of the proportion of MPs and TF+MPs values, the area under the receiver operating characteristic curves was estimated to be 0.836 and 0.828, respectively. Overall, experts concluded that in the prediction of VTE related to lung cancer, an elevated proportion of MPs and TF+MPs might be helpful.