Kanis SL, Modderman S, Escher JC, et al. - Researchers sought to report on the long-term health outcomes of children born to mothers with inflammatory bowel disease (IBD). In addition, they investigated how maternal IBD medication use affects these outcomes. A multicentre retrospective study was conducted in the Netherlands including 1,000 children born to 626 mothers (381 (61%) Crohn’s disease, 225 (36%) ulcerative colitis and 20 (3%) IBD unclassified). Intrauterine exposure to anti-tumour necrosis factor-α (anti-TNF-α) was recorded in 196 children (20%) (60 with concomitant thiopurine) and there were 240 children (24%) with exposure to thiopurine monotherapy. Per outcomes, in utero exposure to anti-TNF-α and/or thiopurine does not correlate with the long-term outcomes, antibiotic-treated infections, severe infections needing hospital admission, adverse reactions to vaccinations, growth failure, autoimmune diseases and malignancies.