Findings demonstrate that health care use by individuals with obesity varies across classes.

• Data of participants with obesity and enrolled in the CONSTANCES cohort were used to report real-life health care use across obesity classes.

• Using the Universal Health Insurance database, information was collected on health care use (defined as ≥1 visit to general practitioners, specialists, emergency departments, and inpatient hospital admissions vs none over a 3-year period prior to enrollment).

• Of 10,774 obese participants, 613 (5.7%) had class III obesity, and 2,076 (19.3%) had class II obesity.

• Higher odds of visiting emergency departments (OR = 1.31) and various specialist physicians (pneumologists, endocrinologists, cardiologists) but lower odds of visiting gynecologists (OR = 0.69) were observed in class III obesity participants vs those with class I obesity.

• Lower odds of visiting general practitioners, dentists, and psychiatrists were reported in participants with class II obesity.

• Regarding hospital admissions, no differences were present.