Talib R, Alnadhari I, Canguven O, et al. - This research sought to explore diabetes mellitus as a risk factor for penile prosthesis implantation infection and the relationship between haemoglobinA1c levels and infection rates. Between January 2012 and November 2019, 599 diabetic patients with erectile dysfunction who had undergone penile prosthesis implantation surgery at Hamad Medical Corporation, Qatar, were included in this retrospective observational study. In this analysis, limitations include retrospective single-centre design and low-infection rates decreasing sample number. The results showed that the penile prosthesis implantation infection rate in a large series of diabetic patients was low with no significant relationship between haemoglobinA1c level and penile prosthesis implantation infection observed.