Gestational diabetes and the risk of late stillbirth: A case–control study from England, UK
BJOG: An International Journal of Obstetrics and Gynaecology Mar 27, 2019
Stacey T, et al. - In prospective case–control study, researchers performed causal mediation analysis to investigate how (i) ‘at risk’ of gestational diabetes mellitus (GDM) and screening for GDM and (ii) raised fasting plasma glucose (FPG) (≥5.6 mmol/l) and clinical diagnosis of GDM jointly influence the risks of late stillbirth. The study population comprised women who had a stillbirth ≥28 weeks of gestation (n = 291) and women with an ongoing pregnancy at the time of interview (n = 733). Outcomes revealed higher risk of late stillbirth among women ‘at risk’ of GDM and/or with raised FPG experience. These risks can be largely decreased with appropriate screening, diagnosis, and the presumed management and care practices that result. However, many women with borderline hyperglycaemia remain exposed to avoidably elevated risk due to variation in practice.
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