Genome-wide DNA methylation profiling of articular cartilage reveals significant epigenetic alterations in Kashin-Beck disease and osteoarthritis
Osteoarthritis and Cartilage Aug 19, 2017
Wang W, et al. – The physicians undertook this study to evaluate genome–wide DNA methylation profiles of knee cartilage from patients with Kashin–Beck disease (KBD) and osteoarthritis (OA). Their findings implicated epigenetic dysregulation of a host of genes in KBD and OA. In addition, they reported common causal epigenetic changes shared by KBD and OA.
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