Molina J, et al. - The goal of this paper was to examine the brain activation in adolescents with idiopathic musculoskeletal pain (IMP), with the aid of functional resonance magnetic imaging (fMRI), while performing an experimental paradigm of pain. A greater tendency of requesting higher brain function in cognitive-emotional areas was noted among adolescents with idiopathic musculoskeletal pain (IMP), when interpreting unpredictable sensory-perceptual situations. Hence, it gave rise to the assumption that this difference in pain processing in adolescents with IMP made the subjective experience of pain more intense and unpleasant.