Goraya N, et al. - In this study performed on 108 macroalbuminuric, matched, nondiabetic chronic kidney disease (CKD) patients with metabolic acidosis, researchers investigated if treatment with base-producing fruits and vegetables (F + V) better improves cardiovascular disease (CVD) risk indicators than oral sodium bicarbonate (NaHCO₃). They randomized 36 participants to F + V in amounts to attenuate dietary acid by half, 36 to oral NaHCO₃ (HCO₃) 0.3 mEq/kg bw/day, or 36 to Usual Care (UC). They found that CKD patients treated with F + V or oral NaHCO₃ demonstrated comparable metabolic acidosis improvement and estimated glomerular filtration rate preservation. CVD risk indicators were better improved by F + V, and therefore, it was considered a potentially better option for attenuating CVD risk.