Sadacharam K, et al. - Individuals with neuromuscular scoliosis who were undergoing posterior spinal fusion (PSF) with unit rod fixation were recognized in order to investigate the relationship of fresh frozen plasma (FFP) ratio with blood loss in this elective surgical population. Risk estimation exhibited that individuals in the low FFP group were more prone to lose > 120% blood volume. Linear regression showed that each unit of the rise in the FFP-to-RBC ratio was related to a 27.5% mean decrease in blood volume loss. Therefore, in this retrospective study of complex spine patients who were undergoing PSF, it was discovered that the FFP-to-RBC ratio was important independent predictor of blood loss in this group. Hence, in patients with neuromuscular scoliosis undergoing posterior spine fusion, blood loss could be reduced by the use of a higher ratio of FFP to RBC.