van Kleef MEAM, et al. - In 6,913 adult patients with clinical manifest arterial disease from the Secondary Manifestations of ARTerial disease (SMART) cohort, researchers examined the link between four electrocardiographic left ventricular hypertrophy (ECG-LVH) criteria (Sokolow-Lyon, Cornell product, Cornell/strain index, and Framingham criterion), and risk of cardiovascular events and mortality. They used Cox proportional regression analysis to estimate the risk of the four ECG-LVH criteria and the primary composite outcome that included myocardial infarction, stroke or cardiovascular death, and secondary outcomes such as MI, stroke and all-cause mortality, adjusted for confounders. According to findings, an increased risk of cardiovascular events was observed in relation to all four ECG-LVH criteria. Most likely, the most relevant ECG-LVH criterion for clinical practice is Cornell/strain index as it is both highly prevalent and carries a high cardiovascular risk.