Food insecurity is associated with mortality among U.S. adults with nonalcoholic fatty liver disease and advanced fibrosis
Clinical Gastroenterology and Hepatology Dec 21, 2021
Kardashian A, et al. - In adults with nonalcoholic fatty liver disease (NAFLD) and advanced fibrosis, food insecurity is shown to be significantly linked with greater all-cause mortality. To enhance health in adults with liver disease, interventions that address food insecurity in this population should be prioritized.
Food insecurity represents a growing public health challenge in the U.S. and has been associated with NAFLD and advanced fibrosis.
Using a population-based cohort study of U.S. adults (≥20 years) in the NHANES 1999-2014 with NAFLD and advanced fibrosis, food security was assessed using the Department of Agriculture Food Security Survey Module.
This analysis involved 34,134 eligible participants (mean age 47 years) including 4,816 with NAFLD and 1,654 with advanced fibrosis; food insecurity was present in 28% and 21%, respectively.
In multivariable analyses, food insecurity was found to be independently related to higher mortality in those with NAFLD (HR=1.46) and advanced fibrosis (HR=1.37) and greater outpatient healthcare utilization in NAFLD patients (OR=1.32).
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