Donovan RL, Harries L, Whitehouse MR, et al. - This study was sought to synthesize the available evidence matching flexible nailing vs plating techniques for diaphyseal femoral fractures in children between the ages of 5 and 12. Researchers conducted a systematic review of interventional and observational studies applying MEDLINE, EMBASE, Cochrane CENTRAL, Web of Science, WHO Global Index Medicus, and LILACS. The primary endpoint included complication rates. Rates of individual complications and operative variables (e.g. operative time, blood loss) were considered secondary endpoints. For this age group, data on this topic is limited despite accounting for one-third of paediatric femoral fractures. This study distinguished a significantly elevated relative risk of all complications, and in particular with respect to malunion and prominent metalwork when fractures in this cohort are treated with flexible nails in comparison with plates. A multi-centre randomised trial to ascertain whether either treatment is superior would be verified.