Jonker SMR, et al. - Researchers assessed the long-term changes in endothelial cell density (ECD) following the implantation of 2 types of foldable iris-fixated phakic intraocular lenses (pIOLs) for the treatment of myopia and astigmatism. Over a 5 year period, around 10% was the chronic EC loss in eyes implanted with the foldable myopic (toric) pIOL. As per data, significant EC loss resulted in subsequent pIOL explantation in up to 3.1% of eyes.