Oderich GS, Farber MA, Schneider D, et al. - Researchers sought to report the 5-year results of the prospective, multicenter study aimed at evaluating the Zenith Fenestrated AAA Endovascular Graft (William A. Cook Australia, Brisbane) for juxtarenal abdominal aortic aneurysms (AAAs). From 2005 to 2012, prospective enrollment of 67 patients (54 male, mean age 74±8 years) at 14 United States centers was performed. In patients with infrarenal aortic neck lengths of 4-14 mm, fenestrated stent-grafts were employed to target 178 renal-mesenteric arteries with a mean of 2.7 vessels per patient. At 5 years, the final study follow up was completed by 42 of the 67 patients, with clinical examination obtained in 41 and CT imaging in 39. The 5-year outcomes suggest that Zenith Fenestrated AAA stent-graft is safe and effective with no associated late graft- or aneurysm-related deaths. The most frequent indication for secondary intervention was in-stent stenosis of bare metal renal stents. It was correlated with low rate of type IA endoleak, sac enlargement, and device migration supporting its use in cases with juxtarenal AAAs.