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Fibromyalgia among patients with chronic migraine and chronic tension-type headache: A multicenter prospective cross-sectional study

Headache: The Journal of Head and Face Pain Sep 27, 2017

Cho SJ, et al. - Researchers performed this work to assess the frequency and impact of fibromyalgia (FM) among patients with chronic migraine (CM) and chronic tension-type headache (CTTH). Among patients with CM, FM based on 2010 American College of Rheumatology diagnostic criteria seemed more prevalent in comparison to those with CTTH. Some clinical features and comorbidities of CM varied with the presence of FM.

Methods

  • A cross-sectional study was performed in neurology outpatient clinics of four university hospitals and selected first-visit 136 patients with CM and 35 patients with CTTH.
  • Based on the 2010 American College of Rheumatology diagnostic criteria, researchers assessed FM.

Results

  • Significantly higher frequency of FM was observed among patients with CM when compared to those with CTTH (91/136 [66.9%] vs 9/35 [25.7%], P < .001).
  • As per logistic regression analyses, an increased odds ratio (OR) was evident for FM for patients with CM when compared to those with CTTH after adjustment for age, sex, anxiety, depression, and insomnia (OR = 3.6, 95% confidence interval = 1.1-11.4).
  • Furthermore, in FM Impact Questionnaire, CM patients with FM indicated higher scores compared to CTTH patients with FM (51.5 ± 16.3 vs 43.7 ± 18.7, P = .015).
  • Comorbidity of FM seemed associated with increased frequency of photophobia, phonophobia, anxiety, depression, and insomnia among patients with CM.
  • Patients with CTTH indicated no such association.

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