Ding X, Yang J, Li L, et al. - Along with progress in embryo cryopreservation, particularly the vitrification, more acceptability to freeze all strategy has been recorded than ever before. As per some studies, frozen embryo transfer (FET) has a comparable or higher live birth rate than those observed with fresh embryo transfer (ET) in gonadotropin releasing hormone antagonist (GnRH-ant) protocol. Researchers here retrospectively examined if freeze all strategy in GnRH-a protocol is beneficial for patients, using real-world data. They evaluated women undergoing fresh ET or FET with GnRH-a long protocol at Chongqing Reproductive and Genetics Institute and identified a total of 7,814 patients for inclusion, implementing 5,216 fresh ET cycles and 2,598 FET cycles, respectively. Findings suggest that among infertile patients that underwent in vitro fertilization (IVF) under GnRH-a long protocol, fresh ET vs FET results in higher implantation rate and live birth rate. Based on findings, they emphasize individualizing the freeze all strategy and making it with caution especially with GnRH-a long protocol.