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Fecal markers of intestinal inflammation and intestinal permeability are elevated in Parkinson's disease

Parkinsonism & Related Disorders Mar 01, 2018

Schwiertz A, et al. - Researchers intended to examine if fecal markers of inflammation and impaired intestinal barrier function were implicated in the multifactorial pathogenesis of Parkinson's disease (PD). It was determined that calprotectin, alpha-1-antitrypsin and zonulin could prove to be beneficial non-invasive markers in PD. Despite not being disease-specific, these markers corroborated the hypothesis of an intestinal inflammation as a contributing factor in the pathogenesis of PD.
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