Rogasch JMM, Frost N, Bluemel S, et al. - This study was undertaken to investigate the effect of FDG-PET/CT for pre-therapeutic lymph node staging in non-small cell lung cancer. Researchers designed a monocentric retrospective analysis of pretherapeutic FDG-PET/CT including a total of 247 patients with non small cell lung cancer (NSCLC) (62% male; age, 68 [43-88] years) using an analog or digital PET/CT scanner. In this study, 180 were malignant among 700 L N stations. In this analysis, 93% and 71% were the sensitivity and specificity of PET/CT per LN station. In patients with mediastinal negative PET/CT, 82% of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) procedures could have been omitted by modifying the current guideline workflow as proposed (i.e., restricting EBUS-TBNA in patients with cN0/1 to those with all three risk factors). With different PET/CT scanners, this was consistent. There is a need for prospective confirmation.