Olesen CM, et al. - Researchers conducted this register-based cohort study to identify factors affecting the prognosis of occupational hand eczema. Using files from Labor Market Insurance Denmark, they identified people with hand eczema recognized as an occupational disease (January 2010 to December 2011). Current tobacco smoking and a high level of stress were factors inversely linked to the healing of hand eczema; on the other hand, a high exercise level was significantly associated with healing of eczema. Change of profession was a favorable prognostic factor, while age, sex, atopic dermatitis (AD), contact sensitization, and education did not have significant effects on the prognosis. Overall, traditionally important risk factors like AD and contact sensitization had no significant impact on prognosis, while lifestyle factors were of great significance. The findings suggested that risk factors may vary over time, enabling new prevention perspectives.