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Factors associated with key outcomes in diabetes related foot disease: A prospective observational study

European Journal of Vascular and Endovascular Surgery May 26, 2021

Pena G, Kuang B, Edwards S, et al. - Via performing a prospective observational study of diabetic patients with foot wounds who were admitted to a major tertiary teaching hospital in South Australia or seen at associated multidisciplinary foot clinics, researchers herein investigated limb and patient factors linked with key clinical outcomes in diabetic patients with foot ulcers. They recruited a total of 153 participants and obtained outcome data for 152. Among these patients, a statistically significant correlation was observed between WIfI stage and major amputation (subdistribution hazard ratio [SHR] 2.75), mortality (hazard ratio [HR] 2.60), amputation free survival (odds ratio [OR] 0.32), and wound healing (SHR 0.69). In addition, a statistically significant correlation was evident between time to healing and grip strength (SHR 0.50), and previous amputations (major or minor) (SHR 0.57).

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