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Expression of PD-1 and PD-L1 in poorly differentiated neuroendocrine carcinomas of the digestive system: A potential target for anti-PD-1/PD-L1 therapy

Human Pathology Oct 19, 2017

Roberts JA, et al. - This paper entailed the analysis of the expression of PD-1/PD-L1 pathway in poorly differentiated neuroendocrine carcinomas of the digestive system. PD-1/PD-L1 expression was determined to be a common occurrence in such tumors. Checkpoint blockade targeting the PD-1/PD-L1 pathway could display a potential role in the treatment of the study cohort.
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