Schnoell J, Kadletz L, Jank BJ, et al. - Via retrospectively involving 49 individuals diagnosed with adenoid cystic carcinoma of the salivary gland between 1996 and 2016, researchers studied the expression of inhibitors of apoptosis and their potential prognostic value in adenoid cystic carcinoma. Using immunohistochemistry, the expression of cIAP1, cIAP2, XIAP, Birc6, Livin and Survivin was evaluated and their relationship with survival and prognosis was assessed during a median follow-up of 6.4 years. In adenoid cystic carcinoma patients, high expression of XIAP can be used as a prognosticator for poor survival and poor response to radiotherapy. CIAP1, cIAP2, Livin, Birc6, and Survivin did not have any major correlation with the outcome. High XIAP expression, however, was linked to worse cause-specific survival and worse response to radiotherapy, and in multivariable analysis proved to be an independent marker.