Mentzelopoulos SD, et al. - Researchers investigated if risk of death due to postresuscitation septic shock could be attenuated via exposure to stress-dose steroids during and/or after cardiopulmonary resuscitation. For this purpose, they analyzed two randomized clinical trials that assessed vasopressin, steroids, and epinephrine (VSE) during resuscitation and stress-dose steroids following resuscitation in vasopressor-requiring, in-hospital cardiac arrest. Findings of this reanalysis revealed that a lower risk of postresuscitation lethal septic shock was related to exposure to stress-dose steroids, primarily in the context of a combined VSE intervention.