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Exhaled breath condensate pH determinants in school‐aged children: A population‐based study

Pediatric Allergy and Immunology May 28, 2021

Rama TA, Paciência I, Rufo JC, et al. - The present study was performed to explore the relationship between asthma and exhaled breath condensate (EBC) pH in children while studying potential environmental factors for interstudy variability. Researchers performed a cross-sectional analysis including a total of 613 children, aged 7 to 12 years. Assessments included lung function and they evaluated airway reversibility, exhaled nitric oxide, allergic sensitization, and body mass index. Indoor air quality (IAQ) in children’s classrooms during 5 school days. They established regression models to evaluate the effects of asthma and asthma adjusted to IAQ parameters on EBC pH. This study’s findings demonstrate that environmental factors may influence in addition to individual determinants such as asthma and should be taken into consideration when interpreting EBC pH levels in children.

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