de Paula Gomes CAF, Politti F, de Souza Bacelar Pereira C, et al. - The aim of the present study was to analyze the clinical effects of the inclusion of interferential current therapy (ICT), shortwave diathermy therapy (SDT) and photobiomodulation (PHOTO) into an exercise program in patients with knee osteoarthritis (OA). Researchers performed a prospective, five-arm, randomised, placebo-controlled trial to include 100 volunteers aged 40 to 80 years with knee OA. They assigned individuals into five groups: exercise, exercise + placebo, exercise + ICT, exercise + SDT, and exercise + PHOTO. Western Ontario and McMaster Universities, numerical rating pain scale (NRPS), pressure pain threshold (PPT), self-perceived fatigue and sit-to-stand test, which were assessed before and after 24 treatment sessions at a frequency of three sessions per week were the endpoint measures. The findings suggested that for individuals, the addition of ICT, SDT or PHOTO into an exercise program with knee OA is not superior to exercise performed in isolation in terms of clinical benefit.