Crispi F, Rodríguez-López M, Bernardino G, et al. - Researchers conducted this cohort study to assess baseline cardiac function and structure and exercise capacity in young adults born small for gestational age (SGA). The sample consisted of 81 adults born SGA (median age at study, 34.4 years [IQR, 30.8-36.7 years]; 43 women [53%]) and 77 control candidates (median age at study, 33.7 years [interquartile range (IQR), 31.0-37.1 years]; 33 women [43%]). Cardiac shape analysis exhibited minor changes at rest in right ventricular geometry with preserved cardiac function in individuals born SGA, however, compared with controls, adults born SGA had lower exercise capacity, with reduced maximal workload and oxygen consumption. Exercise capacity was found to be significantly related to left ventricular mass. This cohort of SGA-born young adults had significantly reduced exercise capacity. Such findings support further investigation into the causes of impaired exercise capacity and the potential link to increased cardiovascular mortality in adults born SGA.