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Evolving trends in adult heart transplant with the 2018 heart allocation policy change

JAMA Cardiology Feb 11, 2021

Kilic A, Mathier MA, Hickey GW, et al. - Researchers sought to report on the changes in patient characteristics, wait list outcomes, and posttransplant outcomes after implementation of the new heart allocation policy on October 18, 2018. From the United Network for Organ Sharing multicenter, national registry, they reviewed all 15,631 adults receiving heart transplants, excluding multiorgan transplants, in the US. The heart allocation policy change has now resulted in transplantation in higher-risk recipients, with higher rates of bridging with temporary mechanical circulatory support. They noted improvement in wait list outcomes, including decreases in wait list mortality and increases in rates of transplant. However, there was a decrease in posttransplant 1-year survival from 92.1% to 87.5%. Persistence in these trends was noted to 1-year follow-up, highlighting the relevance of continued reevaluation of the new heart allocation policy.

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