Evidence on the acute and residual neurocognitive effects of cannabis use in adolescents and adults: A systematic meta‐review of meta‐analyses
Addiction Jan 28, 2022
According to meta-analytical data, cannabis intoxication results in small to moderate deficits in various cognitive domains. These acute impairments accord with reported residual impacts, indicating that cannabis-induced detrimental impacts persist beyond acute intake.
Researchers undertook this meta-review to assess the magnitude of acute and residual impacts of cannabis on cognition in adolescents and adults afforded by meta-analyses as well as to assess quality of evidence.
By exploring PubMed, PsycINFO, Web of Science and Google Scholar, a total of 10 eligible meta-analyses (71 effects sizes, n = 43 761) were found with evidence ranging from low to moderate quality.
The most strong evidence was found for verbal learning and memory, and these were most impaired by acute cannabis intoxication that persisted after intoxication passed.
For executive functioning, small-to-moderate acute and residual adverse impacts were documented.
Small deficits in inhibitory processes and flexibility as well as small-to-moderate deficits in working memory and decision-making were brought about by cannabis use.
Evidence concerning processing speed and attention has demonstrated that cannabis use caused small-to-moderate adverse impacts and residual neurocognitive deficits developed in heavy cannabis-using youths.
Findings revealed no significant difference between cannabis users and non-users on language, and small-to-moderate impacts for simple motor skills.
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