Ahn SJ, et al. - Researchers examined if ultra-widefield fundus autofluorescence (UWF-FAF) imaging is valuable for evaluating hydroxychloroquine (HCQ) retinopathy. In addition, they report peripheral autofluorescence findings in Asian patients with this condition. They studied 58 eyes of 29 patients with HCQ retinopathy in this retrospective study. Forty-one of 58 eyes (70.7%) with HCQ retinopathy exhibited abnormal FAF findings in the retinal periphery outside the field of view of conventional FAF as hypoautofluorescent (23 eyes, 39.7%) and hyperautofluorescent (38 eyes, 65.5%) lesions. Findings revealed variation in peripheral autofluorescence findings in eyes with HCQ retinopathy according to the severity of the retinopathy. Functional correlation of the retinal findings with UWF-FAF to visual field results was observed. Findings suggest a possible utility of UWF-FAF for evaluating HCQ retinopathy, particularly in Asian patients.