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Evaluation of focal laser ablation of prostate cancer using high spectral and spatial resolution imaging: A pilot study

Journal of Magnetic Resonance Imaging Apr 17, 2019

Wang S, et al. - In this prospective study involving 14 patients with biopsy-confirmed localized prostate cancers, researchers assessed the feasibility of imaging with high spectral and spatial resolution using a multiecho gradient echo (MEGE) MRI to identify ablation zones after prostate cancer focal laser ablation (FLA), a minimally invasive thermal ablation to induce coagulative necrosis in cancer. FLA was performed with a 1.5 T MRI scanner under conscious sedation monitoring. From the MEGE data, the T2 maps and water resonance peak height (WPH) images were calculated. Findings suggested that T2 and WPH images provide acceptable ablation zones measurements during FLA treatment of prostate cancers without the need for contrast agent injection. This could allow repeated evaluation after each heating period in order to optimize subsequent ablations.
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