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Evaluation of a routine point-of-care intervention for early infant diagnosis of HIV: An observational study in eight African countries

The Lancet HIV Jun 03, 2019

Bianchi F, et al. - Researchers assessed key service delivery and clinical outcomes in eight countries (Cameroon, Côte d'Ivoire, Kenya, Lesotho, Mozambique, Rwanda, Swaziland, and Zimbabwe), before and after a point-of-care (POC) intervention was introduced for early infant diagnosis (EID) of HIV. In addition, they compared the costs of POC vs conventional EID of HIV. From November 14, 2016 to November 26, 2017, they retrospectively collected data on clinical and service delivery outcomes of conventional testing at 96 health-care facilities using conventional testing for tests done between March 3, 2014, and March 30, 2017. Between December 1, 2016 and December 31, 2017, POC tests were done at 339 health-care facilities. The analysis revealed an improved speed of return of HIV test results in addition to earlier ART initiation in correlation to POC EID implementation. Potential reduction in morbidity and mortality in infants with HIV could be achieved with this approach. They emphasize considering POC EID as a preferred testing strategy for implementation by funders and implementing partners.

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