Noe MH, Wan MT, Mostaghimi A, et al. - Researchers aimed to describe the patient characteristics and the disease course among patients with generalized pustular psoriasis (GPP) across the United States.

• A retrospective case series of 95 adults with GPP.

• Of patients, 70.5% were women with a mean age of 50.3 years.

• On initial presentation, more than one-third of patients were hospitalized, and two-third received treatment with systemic therapies; over time, hospitalizations were required in 35.8% of patients for disease flares.

• Risk of an emergency department or hospital encounter appeared lower for women.

• Overall GPP is a rare, chronic disease with no standard therapy and is linked with continued healthcare utilization over time.